{"id":4346,"date":"2024-05-24T17:05:42","date_gmt":"2024-05-24T09:05:42","guid":{"rendered":"https:\/\/transnovo.com\/news\/%e5%b9%b2%e8%b4%a7%e6%bb%a1%e6%bb%a1-%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e9%92%88%e5%af%b9%e8%82%be%e8%84%8f%e4%bd%8e%e6%b8%a9%e6%9c%ba%e6%a2%b0%e7%81%8c%e6%b3%a8%e7%9a%84%e5%ae%9e%e6%93%8d\/"},"modified":"2024-05-29T11:58:15","modified_gmt":"2024-05-29T03:58:15","slug":"%e5%b9%b2%e8%b4%a7%e6%bb%a1%e6%bb%a1-%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e9%92%88%e5%af%b9%e8%82%be%e8%84%8f%e4%bd%8e%e6%b8%a9%e6%9c%ba%e6%a2%b0%e7%81%8c%e6%b3%a8%e7%9a%84%e5%ae%9e%e6%93%8d","status":"publish","type":"post","link":"https:\/\/transnovo.com\/en\/news\/%e5%b9%b2%e8%b4%a7%e6%bb%a1%e6%bb%a1-%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e9%92%88%e5%af%b9%e8%82%be%e8%84%8f%e4%bd%8e%e6%b8%a9%e6%9c%ba%e6%a2%b0%e7%81%8c%e6%b3%a8%e7%9a%84%e5%ae%9e%e6%93%8d\/","title":{"rendered":"\u5e72\u8d27\u6ee1\u6ee1 | \u65b0\u7248\u6307\u5357\u9488\u5bf9\u80be\u810f\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u7684\u5b9e\u64cd\u5efa\u8bae\uff08\u4e0a\uff09"},"content":{"rendered":"
\n

\u968f\u7740\u8fb9\u7f18\u4f9b\u4f53\u7684\u65e5\u76ca\u589e\u591a\uff0c\u80be\u810f\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u6280\u672f\uff08hypothermic machine perfusion, HMP\uff09\u7684\u5e94\u7528\u65e5\u76ca\u666e\u53ca\u3002HMP\u5177\u6709\u8bc4\u4f30\u80be\u810f\u8d28\u91cf\u3001\u6e05\u9664\u6b8b\u5b58\u8840\u6813\u3001\u6539\u5584\u80be\u810f\u5fae\u5faa\u73af\u3001\u51cf\u5c11\u79fb\u690d\u7269\u529f\u80fd\u5ef6\u8fdf\u6062\u590d\uff08delayed graft function, DGF\uff09\u53d1\u751f\u7684\u4f5c\u7528\uff0c\u5f97\u5230\u4e34\u5e8a\u4e13\u5bb6\u7684\u5e7f\u6cdb\u8ba4\u53ef\u3002<\/p>\n

2024\u7248\u300a\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u4fdd\u5b58\u6307\u5357\u300b\u9488\u5bf9HMP\u76f8\u5173\u768411\u4e2a\u4e34\u5e8a\u95ee\u9898\u63d0\u51fa\u4e86\u660e\u786e\u7684\u63a8\u8350\u610f\u89c1\u53ca\u8bc1\u636e\u7b49\u7ea7\u3002\u5176\u4e2d\u5305\u62ec\u201cHMP\u4f7f\u7528\u9002\u5e94\u8bc1\u3001\u63a8\u8350\u704c\u6ce8\u538b\u529b\u3001\u704c\u6ce8\u65f6\u95f4\u3001\u704c\u6ce8\u52a0\u836f\u3001\u591a\u652f\u52a8\u8109\u704c\u6ce8\u201d\u7b49\u4e34\u5e8a\u6700\u5e38\u5173\u6ce8\u7684\u95ee\u9898\u3002<\/p>\n

\u95ee\u98981\uff1aLifePort\u704c\u6ce8\u538b\u529b\u63a8\u8350<\/p>\n

\u63a8\u8350\u610f\u89c1\uff1a<\/span><\/p>\n

\u6b63\u5e38\u60c5\u51b5\u4e0b\uff0c\u63a8\u8350LifePort\u7684\u704c\u6ce8\u538b\u529b30mmHg\uff0c\u513f\u7ae5\u4f9b\u80be\u9700\u9002\u5f53\u964d\u4f4e\u704c\u6ce8\u538b\u529b\uff08\u63a8\u8350\u5f3a\u5ea6B\uff0c\u8bc1\u636e\u7b49\u7ea72a\uff09\u3002<\/p>\n

\u5bf9\u4e8eECD\u4f9b\u80be\u3001\u704c\u6ce8\u4e0d\u826f\u4f9b\u80be\u3001\u704c\u6ce8\u53c2\u6570\u4e0d\u4f73\u7684\u4f9b\u80be\uff0c\u53ef\u4ee5\u9002\u5ea6\u63d0\u9ad8\u704c\u6ce8\u538b\u529b\u81f330\uff5e40mmHg\uff0c\u4f46\u9700\u6ce8\u610f\u957f\u65f6\u95f4\u9ad8\u704c\u6ce8\u538b\u529b\u5bf9\u80be\u810f\u7684\u635f\u4f24\uff08\u63a8\u8350\u5f3a\u5ea6B\uff0c\u8bc1\u636e\u7b49\u7ea72a\uff09<\/span>.<\/p>\n

\u95ee\u98982\uff1aHMP\u704c\u6ce8\u65f6\u95f4\u63a8\u8350<\/p>\n

\u63a8\u8350\u610f\u89c1\uff1a<\/span><\/p>\n

\u5efa\u8baeHMP\u704c\u6ce8\u65f6\u95f4\u81f3\u5c11\u22652h\uff08\u704c\u6ce82h\u540e\u6574\u4f53\u704c\u6ce8\u53c2\u6570\u8d8b\u4e8e\u7a33\u5b9a\uff09<\/span>\uff1b<\/p>\n

\u82e5\u704c\u6ce8\u53c2\u6570\u6ee1\u610f\uff08\u963b\u529b\u6307\u6570\uff1c0.3 mmHg\/\uff08ml\u00b7min\uff09\uff0c\u704c\u6ce8\u6d41\u91cf\uff1e100 ml\/min\uff09\uff0c\u53ef\u968f\u65f6\u7ec8\u6b62\u704c\u6ce8\uff08\u63a8\u8350\u5f3a\u5ea6 B\uff0c\u8bc1\u636e\u7b49\u7ea7 2a<\/span>\uff09\u3002<\/p>\n

\u82e5\u704c\u6ce8\u53c2\u6570\u4e0d\u4f73\uff0c\u6216\u662fECD\/\u539f\u4f4d\u704c\u6ce8\u4e0d\u826f\u7b49\u4f9b\u80be\uff0c\u6839\u636e\u963b\u529b\u53ca\u6d41\u91cf\u7684\u53d8\u5316\u51b3\u5b9a\u704c\u6ce8\u65f6\u95f4\uff0c\u5efa\u8bae\u704c\u6ce8\u4e0d\u8d85\u8fc724h\uff08\u63a8\u8350\u5f3a\u5ea6B\uff0c\u8bc1\u636e\u7b49\u7ea72a\uff09<\/span>.<\/p>\n

\u95ee\u98983\uff1a\u5982\u4f55\u5e94\u7528HMP\u53c2\u6570\u8bc4\u4ef7\u80be\u810f\u8d28\u91cf<\/p>\n

\u63a8\u8350\u610f\u89c1\uff1a<\/span><\/p>\n

1\uff09 HMP\u53c2\u6570\u8bc4\u4ef7\u4f9b\u80be\u8d28\u91cf\u7684\u5177\u4f53\u6807\u51c6\u89c1\u4e0b\u88681\uff08\u63a8\u8350\u5f3a\u5ea6 B\uff0c\u8bc1\u636e\u7b49\u7ea7 2a\uff09<\/span><\/p>\n

\u88681\uff1aHMP\u53c2\u6570\u8bc4\u4f30\u4f9b\u80be\u8d28\u91cf\u7684\u6807\u51c6
\nTips\uff1a\u4e0d\u4e3b\u5f20\u5355\u7eaf\u4f7f\u7528\u704c\u6ce8\u53c2\u6570\u6765\u5224\u65ad\u4f9b\u80be\u80fd\u5426\u79fb\u690d\uff0c\u9700\u7ed3\u5408\u4f9b\u8005\u60c5\u51b5\u3001\u4f9b\u80be\u75c5\u7406\u7b49\u7efc\u5408\u8bc4\u4ef7\u3002<\/p>\n

2\uff09\u5efa\u8bae\u6839\u636e\u7ec8\u672b\u963b\u529b\u6307\u6570\u3001\u6d41\u91cf\u3001\u704c\u6ce8\u65f6\u95f4\u5206\u5c42\u6253\u5206\uff0c\u4ee5\u7efc\u5408\u8bc4\u4ef7\u80be\u810f\u8d28\u91cf\u3002\u5177\u4f53\u8bc4\u5206\u6807\u51c6\u89c1\u4e0b\u88682\uff08\u63a8\u8350\u5f3a\u5ea6B\uff0c\u8bc1\u636e\u7b49\u7ea72b\uff09<\/span><\/p>\n

\u7efc\u5408\u8bc4\u5206\uff1c4\u5206\uff0c\u8d28\u91cf\u826f\u597d\uff1b\u8bc4\u52064\uff5e7\u5206\uff0c\u8d28\u91cf\u53ef\uff1b\u8bc4\u52068\uff5e11\u5206\uff0c\u8d28\u91cf\u4e00\u822c\uff1b\u8bc4\u5206\uff1e11\u5206\uff0c\u8d28\u91cf\u5dee\uff0c\u5efa\u8bae\u614e\u91cd\u4f7f\u7528\uff0c\u4ecd\u9700\u7ed3\u5408\u4f9b\u8005\u8bc4\u5206\u3001\u75c5\u7406\u8bc4\u5206\u7b49\u7efc\u5408\u8bc4\u5224\u3002<\/p>\n

HMP\u704c\u6ce8\u53c2\u6570\u4e3a\u65e0\u521b\u6027\u8bc4\u4f30\u4f9b\u80be\u8d28\u91cf\u63d0\u4f9b\u4e86\u652f\u6301\u3002\u4e00\u9879\u7eb3\u5165336\u4f8b\u704c\u6ce8\u4fdd\u5b58\u4f9b\u80be\u7684\u524d\u77bb\u6027\u7814\u7a76\u53d1\u73b0\uff0c\u704c\u6ce8\u7ec8\u672b\u671f\u7684\u963b\u529b\u6307\u6570\u503c\u662f\u672f\u540eDGF\u548c1\u5e74\u79fb\u690d\u7269\u5931\u529f\u7684\u72ec\u7acb\u5371\u9669\u56e0\u7d20\u30101\u3011\u3002\u897f\u9644\u4e00\u901a\u8fc7\u6536\u96c6333\u4f8b\u4f9b\u80be\u53d7\u8005\u7684\u4e34\u5e8a\u3001\u75c5\u7406\u3001\u704c\u6ce8\u53c2\u6570\u7b49\u76f8\u5173\u8d44\u6599\uff0c\u5efa\u7acb\u5305\u542b\u4f9b\u4f53\u8bc4\u5206\u3001\u75c5\u7406\u8bc4\u5206\u3001\u704c\u6ce8\u53c2\u6570\u7684\u8054\u5408\u9884\u6d4b\u6a21\u578b\uff0c\u53d1\u73b0\u704c\u6ce8\u963b\u529b\u3001\u6d41\u91cf\u503c\u4e0e\u60a3\u8005\u4e34\u5e8a\u8bc4\u5206\u53ca\u75c5\u7406\u8bc4\u5206\u5747\u5448\u663e\u8457\u76f8\u5173\u3002\u8054\u5408\u9884\u6d4b\u6a21\u578b\u8bca\u65adDGF\u7684\u66f2\u7ebf\u4e0b\u9762\u79ef\u4e3a0.89\uff0c\u8bca\u65ad\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\u8fbe80%\uff0c\u660e\u663e\u9ad8\u4e8e\u4efb\u610f\u5355\u4e00\u9884\u6d4b\u6307\u6807\u30102\u3011\u3002<\/p>\n

\u95ee\u98984\uff1aLifePort\u6539\u5584\u80be\u810f\u8d28\u91cf\u7684\u65b9\u6cd5\u6709\u54ea\u4e9b<\/p>\n

\u63a8\u8350\u610f\u89c1\uff1a<\/p>\n

1\uff09 \u53ef\u5411\u704c\u6ce8\u6db2\u4e2d\u52a0\u5165\u4e0d\u540c\u79cd\u7c7b\u836f\u7269\uff08\u4e0b\u56fe1\uff09<\/p>\n

2\uff09 \u53ef\u9002\u5ea6\u63d0\u9ad8\u704c\u6ce8\u538b\u529b\uff0c\u4f46\u65f6\u95f4\u4e0d\u5b9c\u8fc7\u957f\uff08\u63a8\u8350\u5f3a\u5ea6 B\uff0c\u8bc1\u636e\u7b49\u7ea7 3a\uff09<\/span><\/p>\n

\u56fe1\uff1aLifePort\u52a0\u836f\u6539\u5584\u80be\u810f\u8d28\u91cf\u7684\u836f\u7269\u79cd\u7c7b<\/p>\n

Reference:
\n\u30101\u3011Jochmans I, Moers C, Smits JM, et al. The prognostic value of renal resistance during hypothermic machine perfusion of deceased donor kidneys [published correction appears in Am J Transplant. 2012 Jan;12(1):267]. Am J Transplant. 2011;11(10):2214-2220. doi:10.1111\/j.1600-6143.2011.03685.x
\n\u30102\u3011Zheng J, Hu X, Ding X, et al. Comprehensive assessment of deceased donor kidneys with clinical characteristics, pre-implant biopsy histopathology and hypothermic mechanical perfusion parameters is highly predictive of delayed graft function. Ren Fail. 2020;42(1):369-376. doi:10.1080\/0886022X.2020.1752716<\/p>\n

2024\u7248\u300a\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u4fdd\u5b58\u6307\u5357\u300b\u94fe\u63a5\uff1a
\nhttps:\/\/mp.weixin.qq.com\/s\/LBH5UyIGfKeXQe-juRw8dw<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

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