{"id":4302,"date":"2024-05-13T14:43:49","date_gmt":"2024-05-13T06:43:49","guid":{"rendered":"https:\/\/transnovo.com\/news\/%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e5%87%ba%e7%82%89-%e4%bb%80%e4%b9%88%e6%a0%b7%e7%9a%84%e7%a7%bb%e6%a4%8d%e8%82%be%e8%84%8f%e9%9c%80%e8%a6%81%e8%bf%9b%e8%a1%8c%e4%bd%93%e5%a4%96%e6%9c%ba\/"},"modified":"2024-05-15T09:13:22","modified_gmt":"2024-05-15T01:13:22","slug":"%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e5%87%ba%e7%82%89-%e4%bb%80%e4%b9%88%e6%a0%b7%e7%9a%84%e7%a7%bb%e6%a4%8d%e8%82%be%e8%84%8f%e9%9c%80%e8%a6%81%e8%bf%9b%e8%a1%8c%e4%bd%93%e5%a4%96%e6%9c%ba","status":"publish","type":"post","link":"https:\/\/transnovo.com\/en\/news\/%e6%96%b0%e7%89%88%e6%8c%87%e5%8d%97%e5%87%ba%e7%82%89-%e4%bb%80%e4%b9%88%e6%a0%b7%e7%9a%84%e7%a7%bb%e6%a4%8d%e8%82%be%e8%84%8f%e9%9c%80%e8%a6%81%e8%bf%9b%e8%a1%8c%e4%bd%93%e5%a4%96%e6%9c%ba\/","title":{"rendered":"\u65b0\u7248\u6307\u5357\u51fa\u7089 | \u4ec0\u4e48\u6837\u7684\u79fb\u690d\u80be\u810f\u9700\u8981\u8fdb\u884c\u4f53\u5916\u673a\u68b0\u704c\u6ce8\uff1f"},"content":{"rendered":"<div class=\"wxsyncmain\">\n<p>\u00a0 \u00a0\u5668\u5b98\u4fdd\u5b58\u65b9\u6cd5\u5bf9\u4e8e\u7ef4\u6301\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u7684\u6d3b\u6027\u975e\u5e38\u91cd\u8981\uff0c\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u4fdd\u5b58\u6280\u672f\uff08hypothermic machine perfusion, HMP\uff09\u5177\u6709\u8bc4\u4f30\u80be\u810f\u8d28\u91cf\u3001\u6e05\u9664\u6b8b\u5b58\u8840\u6813\u3001\u6539\u5584\u80be\u810f\u5fae\u5faa\u73af\u3001\u51cf\u5c11\u79fb\u690d\u7269\u529f\u80fd\u5ef6\u8fdf\u6062\u590d\uff08delayed graft function, DGF\uff09\u53d1\u751f\u7684\u4f5c\u7528\uff0c\u5f97\u5230\u4e34\u5e8a\u4e13\u5bb6\u7684\u5e7f\u6cdb\u8ba4\u53ef\u3002\u7136\u800c\uff0c\u7a76\u7adf\u4ec0\u4e48\u6837\u7684\u4f9b\u80be\u9700\u8981\u8fdb\u884cHMP\uff0c\u4e0d\u540c\u4e2d\u5fc3\u7684\u4e34\u5e8a\u5b9e\u8df5\u4ecd\u5b58\u5728\u5dee\u5f02\u3002\u672c\u6b21\u7248\u5e03\u7684\u300a\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u4fdd\u5b58\u6307\u5357\u300b\u57282016 \u7248\u80be\u810fHMP\u4e13\u5bb6\u5171\u8bc6\u30012019\u7248\u80be\u810fHMP\u64cd\u4f5c\u89c4\u8303\u7684\u57fa\u7840\u4e0a\uff0c\u7ed3\u5408\u73b0\u4eca\u4e34\u5e8a\u6700\u4e3a\u5173\u6ce8\u768411\u4e2a\u4e34\u5e8a\u5b9e\u9645\u95ee\u9898\uff0c\u5236\u8ba2\u4e86\u672c\u6307\u5357\u3002\u5176\u4e2d\uff0c\u5bf9\u4e8e\u80be\u810fHMP\u7684\u704c\u6ce8\u6807\u51c6\uff0c\u6307\u5357\u8fdb\u884c\u4e86\u660e\u786e\u7684\u9002\u5e94\u8bc1\u4e0e\u8bc1\u636e\u7b49\u7ea7\u63a8\u8350\u3002<\/p>\n<p>\u4e34\u5e8a\u610f\u89c1\uff1a<br \/>\n\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u5e94\u7528HMP\u7684\u9002\u5e94\u8bc1\u6709\u54ea\u4e9b\uff1f<\/p>\n<p>\u63a8\u8350\u610f\u89c1\uff1a<br \/>\n1) \u6269\u5927\u6807\u51c6\u4f9b\u8005\u4f9b\u80be\uff08expanded criteria donor, ECD\uff09<br \/>\n2) \u5fc3\u810f\u6b7b\u4ea1\u5668\u5b98\u6350\u732e\u4f9b\u80be\uff08donation after cardiac death, DCD\uff09<br \/>\n3) \u4f9b\u4f53\u6709\u5fc3\u80ba\u590d\u82cf\u53f2\/\u4f4e\u8840\u538b\u8fc7\u7a0b<br \/>\n4) \u4f9b\u80be\u51b7\u7f3a\u8840\u65f6\u95f4\u8f83\u957f<br \/>\n5) \u4f9b\u80be\u83b7\u53d6\u8fc7\u7a0b\u4e2d\u5b58\u5728\u704c\u6ce8\u4e0d\u826f<\/p>\n<p>\u5b58\u5728\u4e0a\u8ff05\u9879\u60c5\u51b5\u4e4b\u4e00\u7684\u9057\u4f53\u6350\u732e\u4f9b\u80be\uff0c\u5efa\u8bae\u4f7f\u7528HMP\u5bf9\u80be\u810f\u8fdb\u884c\u79bb\u4f53\u4fdd\u5b58\uff08\u63a8\u8350\u5f3a\u5ea6A\uff0c\u8bc1\u636e\u7b49\u7ea71a\uff09\u3002<\/p>\n<p>\u5728\u80be\u810fHMP\u76f8\u5173\u7684\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u53d1\u8868\u6587\u7ae0\u5f71\u54cd\u529b\u6700\u9ad8\u7684\u5f53\u5c5e\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\u3002NEJM\u66fe\u4e8e2009\u30012012\u30012023\u5e74\u5206\u522b\u62a5\u9053HMP\u4e0e\u9759\u6001\u51b7\u4fdd\u5b58\uff08static cold storage, SCS\uff09\u76f8\u6bd4\u8f83\u7684\u5927\u89c4\u6a21\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u7814\u7a76\uff0c\u7ed3\u679c\u663e\u793a\u57fa\u4e8eLifePort\u7684HMP\u80fd\u663e\u8457\u964d\u4f4e\u80be\u79fb\u690d\u672f\u540eDGF\u53d1\u751f\u7387\uff0c\u63d0\u9ad8\u79fb\u690d\u80be1\u5e74\u548c3\u5e74\u5b58\u6d3b\u7387\u30101-3\u3011\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img aligncenter\" style=\"vertical-align: middle; width: 100%;\" src=\"http:\/\/transnovo.com\/wp-content\/uploads\/2024\/05\/wxsync-2024-05-948b0824c3dddf20117a4bc7e5e5bed7.png\" data-imgfileid=\"100004076\" data-ratio=\"0.44776119402985076\" data-s=\"300,640\" data-type=\"png\" data-w=\"1005\" \/>\u56fe1\uff1aNEJM\u6587\u7ae0\u4e2d\u4e24\u7ec4\u60a3\u8005\u672f\u540eDGF\u53d1\u751f\u53ca\u5b58\u6d3b\u7387\u6bd4\u8f83\u30101-2\u3011<\/p>\n<p>ECD\u4f9b\u80be\u4e8e2002\u5e74\u83b7\u7f8e\u56fd\u5668\u5b98\u83b7\u53d6\u79fb\u690d\u7f51\u7edc\uff08Organ Procurement and Transplantation Network, OPTN\uff09\u8bba\u8bc1\u5ba1\u6279\uff0c\u5c06\u5176\u4f5c\u4e3a\u8bc4\u4f30\u4f9b\u4f53\u80be\u810f\u8d28\u91cf\u7684\u4e00\u4e2a\u6307\u6807\u3002ECD\u7684\u5224\u65ad\u6807\u51c6\u6709\u4e24\u6761\uff0c\u5177\u4f53\u89c1\u5982\u4e0b\u8868\u683c\u30104\u3011\uff1a<\/p>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img aligncenter\" style=\"vertical-align: middle; width: 100%;\" src=\"http:\/\/transnovo.com\/wp-content\/uploads\/2024\/05\/wxsync-2024-05-07e28bed90b010936d0ffc0c25169ccd.png\" data-imgfileid=\"100004077\" data-ratio=\"0.5324074074074074\" data-s=\"300,640\" data-type=\"png\" data-w=\"1080\" \/><\/p>\n<p>ECD\u4f9b\u80be\u5bf9\u51b7\u3001\u70ed\u7f3a\u8840\u635f\u4f24\u7684\u8010\u53d7\u6027\u8f83\u5dee\uff0c\u79fb\u690d\u672f\u540e\u53d1\u751fDGF\u7684\u6982\u7387\u660e\u663e\u589e\u591a\uff0c\u957f\u671f\u5b58\u6d3b\u7387\u8f83\u6807\u51c6\u4f9b\u4f53\u660e\u663e\u964d\u4f4e\u3002\u4e00\u9879\u56fd\u9645\u591a\u4e2d\u5fc3\u968f\u673a\u5bf9\u7167\u7814\u7a76\u5171\u7eb3\u5165182\u4f8bECD\u4f9b\u80be\u53d7\u8005\uff0c\u7ed3\u679c\u8868\u660eHMP\u53ef\u663e\u8457\u964d\u4f4eECD\u80be\u79fb\u690d\u672f\u540eDGF\u53d1\u751f\u98ce\u9669\u3002HMP\u7ec4\u53d7\u80051\u5e74\u79fb\u690d\u7269\u5b58\u6d3b\u7387\u4e3a92.3%\uff0c\u5bf9\u7167\u7ec4\u4ec5\u4e3a80.2%\uff08\u56fe2a\uff09\u3002\u5728\u672f\u540e\u53d1\u751f\u4e86DGF\u7684\u60a3\u8005\u4e2d\uff0cHMP\u5bf9\u79fb\u690d\u72691\u5e74\u5b58\u6d3b\u7387\u7684\u63d0\u5347\u76f8\u6bd4\u5bf9\u7167\u7ec4\u66f4\u662f\u9ad8\u8fbe44%\uff08\u56fe2b\uff09\u30105\u3011\u3002\u800c\u53d1\u8868\u5728NEJM\u76843\u5e74\u968f\u8bbf\u6587\u7ae0\u4ea6\u63d0\u793a\uff0cHMP\u5c06ECD\u4f9b\u80be\u672f\u540e3\u5e74\u7684\u79fb\u690d\u7269\u5b58\u6d3b\u7387\u63d0\u5347\u4e8610%\u30102\u3011\u3002<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"rich_pages wxw-img aligncenter\" style=\"vertical-align: middle; width: 100%;\" src=\"http:\/\/transnovo.com\/wp-content\/uploads\/2024\/05\/wxsync-2024-05-0fe2f558373a3d2fdd824d4957259aa1.png\" data-imgfileid=\"100004078\" data-ratio=\"0.4212962962962963\" data-s=\"300,640\" data-type=\"png\" data-w=\"1080\" \/>\u56fe2\uff1aECD\u4f9b\u80be\u79fb\u690d\u672f\u540e1\u5e74\u5b58\u6d3b\u7387\u6bd4\u8f83<\/p>\n<p>DCD\u4f9b\u80be\u7ecf\u5386\u7684\u70ed\u7f3a\u8840\u635f\u4f24\u548c\u79fb\u690d\u80be\u9884\u540e\u5b58\u5728\u5bc6\u5207\u5173\u8054\u3002\u6cd5\u56fd\u3001\u8377\u5170\u7b49\u591a\u56fd\u5c06DCD\u80be\u810f\u4f5c\u4e3aHMP\u7684\u63a8\u8350\u9002\u5e94\u8bc1\u4e4b\u4e00\uff0c\u7f8e\u56fd\u591a\u5bb6OPO\u4ea6\u5c06DCD\u80be\u810f\u4f5c\u4e3a\u704c\u6ce8\u6807\u51c6\u4e4b\u4e00\u3002\u4e00\u9879\u7eb3\u516516\u9879\u4e34\u5e8a\u7814\u7a76\u3001\u51712266\u4f8b\u53d7\u8005\u7684Meta\u5206\u6790\u53d1\u73b0\uff0cHMP\u53ef\u660e\u663e\u964d\u4f4eDCD\u4f9b\u80be\u672f\u540eDGF\u7684\u53d1\u751f\u98ce\u9669\u30106\u3011\u3002\u6211\u56fd\u4e00\u9879\u7eb3\u5165340\u4f8b\u80be\u79fb\u690d\u53d7\u8005\u7684\u56de\u987e\u6027\u7814\u7a76\u4ea6\u663e\u793a\uff0c\u7ecf\u8fc7HMP\u7684DCD\u4f9b\u80be\u672f\u540eDGF\u53d1\u751f\u7387\u4e3a11.2%\uff08\u5bf9\u7167\u7ec4\u4e3a24.1%\uff09\uff0c\u4e14HMP\u7ec4\u60a3\u8005\u808c\u9150\u6062\u590d\u6b63\u5e38\u7684\u65f6\u95f4\u660e\u663e\u7f29\u77ed\u30107\u3011\u3002<\/p>\n<p>Reference:<br \/>\n\u30101\u3011Moers C, Smits JM, Maathuis MH, et al. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med. 2009;360(1):7-19. doi:10.1056\/NEJMoa0802289<br \/>\n\u30102\u3011Moers C, Pirenne J, Paul A, Ploeg RJ; Machine Preservation Trial Study Group. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med. 2012;366(8):770-771. doi:10.1056\/NEJMc1111038<br \/>\n\u30103\u3011Malinoski D, Saunders C, Swain S, et al. Hypothermia or Machine Perfusion in Kidney Donors. N Engl J Med. 2023;388(5):418-426. doi:10.1056\/NEJMoa2118265<br \/>\n\u30104\u3011Metzger RA, Delmonico FL, Feng S, Port FK, Wynn JJ, Merion RM. Expanded criteria donors for kidney transplantation. Am J Transplant. 2003;3 Suppl 4:114-125. doi:10.1034\/j.1600-6143.3.s4.11.x<br \/>\n\u30105\u3011Treckmann J, Moers C, Smits JM, et al. Machine perfusion versus cold storage for preservation of kidneys from expanded criteria donors after brain death. Transpl Int. 2011;24(6):548-554. doi:10.1111\/j.1432-2277.2011.01232.x<br \/>\n\u30106\u3011Tingle SJ, Figueiredo RS, Moir JA, Goodfellow M, Talbot D, Wilson CH. Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation. Cochrane Database Syst Rev. 2019;3(3):CD011671. Published 2019 Mar 15. doi:10.1002\/14651858.CD011671.pub2<br \/>\n\u30107\u3011\u9879\u548c\u7acb,\u859b\u6b66\u519b,\u7530\u666e\u8bad,\u7b49. \u673a\u68b0\u704c\u6ce8\u5728\u516c\u6c11\u901d\u4e16\u540e\u5668\u5b98\u6350\u732e\u80be\u79fb\u690d\u4e2d\u7684\u5e94\u7528[J]. \u4e2d\u534e\u5668\u5b98\u79fb\u690d\u6742\u5fd7,2015,36(6):330-334. DOI:10.3760\/cma.j.issn.0254-1785.2015.06.002.<\/p>\n<p>&nbsp;<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u00a0\u5668\u5b98\u4fdd\u5b58\u65b9\u6cd5\u5bf9\u4e8e\u7ef4\u6301\u9057\u4f53\u5668\u5b98\u6350\u732e\u4f9b\u80be\u7684\u6d3b\u6027\u975e\u5e38\u91cd\u8981\uff0c\u4f53\u5916\u4f4e\u6e29\u673a\u68b0\u704c\u6ce8\u4fdd\u5b58\u6280\u672f\uff08hypothermic m [&hellip;]<\/p>","protected":false},"author":6,"featured_media":4297,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u65b0\u7248\u6307\u5357\u51fa\u7089 | \u4ec0\u4e48\u6837\u7684\u79fb\u690d\u80be\u810f\u9700\u8981\u8fdb\u884c\u4f53\u5916\u673a\u68b0\u704c\u6ce8\uff1f - tranSnovo<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/transnovo.com\/en\/news\/\u65b0\u7248\u6307\u5357\u51fa\u7089-\u4ec0\u4e48\u6837\u7684\u79fb\u690d\u80be\u810f\u9700\u8981\u8fdb\u884c\u4f53\u5916\u673a\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u65b0\u7248\u6307\u5357\u51fa\u7089 | \u4ec0\u4e48\u6837\u7684\u79fb\u690d\u80be\u810f\u9700\u8981\u8fdb\u884c\u4f53\u5916\u673a\u68b0\u704c\u6ce8\uff1f - 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