{"id":3253,"date":"2021-08-26T12:00:00","date_gmt":"2021-08-26T04:00:00","guid":{"rendered":"https:\/\/transnovo.com\/news\/%e6%96%b0%e5%86%a0%e5%8f%8a%e9%9d%9e%e6%96%b0%e5%86%a0%e6%9c%9f%e9%97%b4%ef%bc%8c%e4%bb%96%e5%85%8b%e8%8e%ab%e5%8f%b8%e5%89%82%e9%87%8f%e4%b8%aa%e4%bd%93%e5%8c%96%e8%b0%83%e6%95%b4%e5%9b%a0%e7%b4%a0\/"},"modified":"2021-08-26T12:00:00","modified_gmt":"2021-08-26T04:00:00","slug":"%e6%96%b0%e5%86%a0%e5%8f%8a%e9%9d%9e%e6%96%b0%e5%86%a0%e6%9c%9f%e9%97%b4%ef%bc%8c%e4%bb%96%e5%85%8b%e8%8e%ab%e5%8f%b8%e5%89%82%e9%87%8f%e4%b8%aa%e4%bd%93%e5%8c%96%e8%b0%83%e6%95%b4%e5%9b%a0%e7%b4%a0","status":"publish","type":"post","link":"https:\/\/transnovo.com\/en\/news\/%e6%96%b0%e5%86%a0%e5%8f%8a%e9%9d%9e%e6%96%b0%e5%86%a0%e6%9c%9f%e9%97%b4%ef%bc%8c%e4%bb%96%e5%85%8b%e8%8e%ab%e5%8f%b8%e5%89%82%e9%87%8f%e4%b8%aa%e4%bd%93%e5%8c%96%e8%b0%83%e6%95%b4%e5%9b%a0%e7%b4%a0\/","title":{"rendered":"Individualized tacrolimus dose adjustment factors and Bayesian approach during new and non-new crowns"},"content":{"rendered":"
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Reference:<\/p>\n

[1] Belli L S , et al. Protective role of tacrolimus, deleterious role of age and comorbidities in liver transplant recipients with Covid-19: results from the ELITA\/ELTR multi-center European study. Gastroenterology . 2021 ;160(4):1151-1163.e3.<\/p>\n

[2]Khan A R , et al. CYP3A5 gene polymorphisms and their impact on dosage and trough concentration of tacrolimus among kidney transplant patients: a systematic review and meta-analysis.  Pharmacogenomics J . 2020;20(4):553-562. The Pharmacogenomics Journal.<\/p>\n

[3] Clinical significance of personalized tacrolimus dosing by adjusting to donor CYP3A\u2010status in liver transplant recipients.  Br J Clin Pharmacol  . 2021;87(4):1790-1800.<\/p>\n

[4] Brunet M\uff0cet al. Therapeutic drug monitoring of tacrolimus-personalized therapy \uff1asecond consensus report. Ther Drug Monit\uff0c2019\uff0c41\uff083\uff09\uff1a261-307.<\/p>\n

[5] Marquet P , et al. Clinical Pharmacokinetics and Bayesian Estimators for the Individual Dose Adjustment of a Generic Formulation of Tacrolimus in Adult Kidney Transplant Recipients. Clin Pharmacokinet . 2021 ;60(5):611-622.<\/p>\n


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